Inflammatory bowel disease (IBD) is a chronic inflammatory condition affecting the digestive tract and impacting nearly three million people in the U.S. Crohn’s disease and ulcerative colitis are two of the most common forms of IBD. The unpredictable symptoms associated with IBD, which may include diarrhea, abdominal pain, unintended weight loss and fatigue, often create emotional and social challenges for those impacted.

Hidradenitis suppurativa, also known as acne inversa, is a condition that causes painful skin lumps, which are often mistaken for pimples and cysts. These lumps are typically found near hair follicles around sweat glands, including the groin, breasts and armpits. Without treatment, the condition can worsen and cause abscesses, or pockets of pus, that can break open and form scars, and may also lead to the formation of tunnels under the skin, called sinus tracts. Hidradenitis suppurativa can have long-term impacts, including decreased mobility due to scarring and chronic intense pain. An estimated 1% of the U.S. population is living with hidradenitis suppurativa and women are three times more likely than men to develop the condition.

Systemic sclerosis is a rare autoimmune condition that affects connective tissue in the body, typically causing the skin to thicken and tighten. The disease can impact other organs and commonly manifests as interstitial lung disease, which affects the tissue and space around the air sacs of the lungs. Interstitial lung disease caused by systemic sclerosis is known as scleroderma-associated interstitial lung disease (SSc-ILD). Systemic sclerosis impacts approximately 100,000 people in the U.S., with interstitial lung disease occurring in more than half and often associated with a poor prognosis.